Biodemography of Old-Age Mortality in Humans and Rodents
نویسندگان
چکیده
منابع مشابه
Biodemography Comes of Age.
Biodemography has emerged and grown over the last fifteen years, with loyal and farsighted support from its patrons. As it enters what might be called its adolescence as a field, it faces challenges along with abounding opportunities. One challenge is to continue to generate knowledge that contributes to human health and well-being. A second is to insist on high standards of quality control wit...
متن کاملsecuritization of mortality risks in life annuities
insurers have in the past few decades faced longevity risks - the risk that annuitants survive more than expected - and therefore need a new approach to manage this new risk. in this dissertation we survey methods that hedge longevity risks. these methods use securitization to manage risk, so using modern financial and insurance pricing models, especially wang transform and actuarial concepts, ...
15 صفحه اولEvaluation of mortality trajectories in evolutionary biodemography.
An important task in evolutionary biodemography is to determine the schedule of survival and reproduction as the outcome of natural selection acting on life histories. We do this by using a model in which the state of the organism is characterized by mass and accumulated damage, both of which are affected by activity and which affect the rate of mortality. Focusing on growth during the juvenile...
متن کاملSpironolactone and colitis: increased mortality in rodents and in humans.
BACKGROUND Crohn's disease causes intestinal inflammation leading to intestinal fibrosis. Spironolactone is an antifibrotic medication commonly used in heart failure to reduce mortality. We examined whether spironolactone is antifibrotic in the context of intestinal inflammation. METHODS In vitro, spironolactone repressed fibrogenesis in transforming growth factor beta (TGF-β)-stimulated huma...
متن کاملOdor identification and mortality in old age.
The association of olfactory dysfunction with mortality was examined in 1162 older persons without dementia or Parkinson's disease. They completed a standard 12-item test of odor identification and then were followed for a mean of 4.2 years (standard deviation [SD] = 2.6, range: 0-9) during which 321 individuals died (27.6%). The relation of olfactory score to risk of death was assessed in a se...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: The Journals of Gerontology Series A: Biological Sciences and Medical Sciences
سال: 2014
ISSN: 1079-5006,1758-535X
DOI: 10.1093/gerona/glu009